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epsilon-viniferin

Product Name
epsilon-viniferin
CAS No.
62218-08-0
Chemical Name
epsilon-viniferin
Synonyms
e-viniferin;Ε-VINIFERIN;epsilon-viniferin;trans-ε-Viniferin;epsilion-Viniferin;ε-Viniferin Standard;(-)-trans-ε-viniferin;(-)-trans-epsilon-viniferin;ε ?Viniferin,ε-?Viniferin,Inhibitor,inhibit,Cytochrome P450,CYPs,ε?Viniferin;(2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-4-hydroxystyryl]-2,3-dihydrobenzofuran-6-ol
CBNumber
CB91337184
Molecular Formula
C28H22O6
Formula Weight
454.47
MOL File
62218-08-0.mol
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epsilon-viniferin Property

Melting point:
approximate 157℃ (dec.)
storage temp. 
Store at -20°C
solubility 
Soluble in methanol;
form 
Powder
Water Solubility 
sparingly soluble in water
LogP
3.802 (est)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL83550
Product name
ε-Viniferin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$333
Updated
2023/01/07
Cayman Chemical
Product number
25737
Product name
trans-ε-Viniferin
Packaging
500μg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
25737
Product name
trans-ε-Viniferin
Packaging
1mg
Price
$115
Updated
2024/03/01
Biosynth Carbosynth
Product number
FV30429
Product name
epsilon-Viniferin
Packaging
1mg
Price
$140
Updated
2021/12/16
Biosynth Carbosynth
Product number
FV30429
Product name
epsilon-Viniferin
Packaging
2mg
Price
$200
Updated
2021/12/16
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epsilon-viniferin Chemical Properties,Usage,Production

Description

trans-ε-Viniferin is a stilbene polyphenol and dimer of trans-resveratrol that has been found in various red wines and has diverse biological activities. It induces disaggregation of aggregated amyloid-β (1-42) (Aβ42; ) fibrils in a cell-free assay and decreases Aβ42- and IL-1β-induced release of TNF-α and IL-6 in primary mouse neuron and astrocyte cocultures. trans-ε-Viniferin reduces cytotoxicity induced by truncated huntingtin (Htt) in PC12 cells (EC50 = 30 nM). It also reduces production of reactive oxygen species (ROS), mitochondrial dysfunction, and PGC-1α depletion and increases protein levels and deacetylase activity of sirtuin 3 (SIRT3) in cells expressing mutant Htt. trans-ε-Viniferin inhibits calcium-activated chloride channel currents in HT-29 cells (IC50 = ~1 μM). In vivo, trans-ε-viniferin (2 μg per animal) reduces rotavirus-induced secretory diarrhea in mice without affecting the rotaviral infection. Dietary administration of trans-ε-viniferin reduces hepatic triglyceride accumulation and body weight increases in a mouse model of diet-induced obesity.

Uses

ε-Viniferin is a stilbene extract posessing cytotoxic effects and may contain anti-cancer properties.

Definition

ChEBI: (-)-trans-epsilon-viniferin is a stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol. It has a role as a metabolite. It is a member of 1-benzofurans, a polyphenol and a stilbenoid. It is functionally related to a trans-resveratrol. It is an enantiomer of a (+)-trans-epsilon-viniferin.

target

5-HT Receptor | MAO | Antifection

epsilon-viniferin Preparation Products And Raw materials

Raw materials

Preparation Products

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epsilon-viniferin Suppliers

ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
Advantage
58
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View Lastest Price from epsilon-viniferin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
ε-Viniferin 62218-08-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-06

62218-08-0, epsilon-viniferinRelated Search:


  • epsilon-viniferin
  • (-)-5-[[(2R)-2,3-Dihydro-6-hydroxy-2β-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)vinyl]benzofuran]-3α-yl]-1,3-benzenediol
  • (2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-(4-hydroxy-trans-styryl)-2,3-dihydrobenzofuran-6-ol
  • (2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-4-hydroxystyryl]-2,3-dihydrobenzofuran-6-ol
  • [2R,(-)]-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydrobenzofuran-6-ol
  • 5-[(2R,3R)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydrobenzofuran-3-yl]benzene-1,3-diol
  • e-viniferin
  • (-)-trans-epsilon-viniferin
  • epsilion-Viniferin
  • Ε-VINIFERIN
  • ε-Viniferin Standard
  • trans-ε-Viniferin
  • 1,3-Benzenediol, 5-[(2R,3R)-2,3-dihydro-6-hydroxy-2-(4-hydroxyphenyl)-4-[(1E)-2-(4-hydroxyphenyl)ethenyl]-3-benzofuranyl]-
  • (-)-trans-ε-viniferin
  • 5-[(2R,3R)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol
  • ε ?Viniferin,ε-?Viniferin,Inhibitor,inhibit,Cytochrome P450,CYPs,ε?Viniferin
  • 62218-08-0
  • 62218-08-8